One of my close friends is really desperate for a guy, help?

Tell her to wait, because she wouldn't want to settle for someone who's with her due to her desperation. It will lead her to numerous heartbreaks, regret, and a bad rep. Tell her that almost everyone is reliant on expectations, and nothing will come it's way unless it is unexpected. Tell her to enjoy the friends she has now, because once she has a boyfriend, she is most likely to drift from them and warn her that she could lose a wonderful friend like you.